Tag: activity

•Translational data presented at ADA demonstrate icovamenib’s potential to promote muscle preservation and fat reduction, supporting its broader therapeutic utility in obesity and diabetes, including as a complementary therapy alongside GLP-1 receptor agonists to enhance metabolic health outcomes 
• Clinical data presented at ADA from COVALENT-112 show improvements in HbA1c and C-peptide in type 1 diabetes patients treated with icovamenib, with no evidence of immune activation, and inflammatory markers stable or reduced
• Additionally, the Company expanded its Phase I BMF-650 study to evaluate a rapid one-step titration and enhanced weight loss potential with its oral GLP-1 receptor agonist

STAMFORD, Conn., June 05, 2026 (GLOBE NEWSWIRE) -- Oban BioPharma today announced that preclinical data for OBT-676, a lead small-molecule candidate for the treatment of obesity and type 2 diabetes, has been selected for a late-breaking presentation at the upcoming American Diabetes Association (ADA) 86th Scientific Sessions being held from June 5^th-8^th in New Orleans, LA. The study characterizes OBT-676 as a new molecular entity that achieves potent full agonism at the amylin and calcitonin receptors (DACRA) while simultaneously delivering partial agonism across the GLP-1, GIP, and glucagon (Triple-G) pathways. OBT-676 demonstrated significant reduction in food intake and adipose-selective weight loss in the industry-standard rat diet-induced obesity (DIO) model.

NEW YORK, June 05, 2026 (GLOBE NEWSWIRE) --

WHY: Rosen Law Firm, a global investor rights law firm, continues to investigate potential securities claims on behalf of shareholders of PennyMac Financial Services, Inc. (NYSE: PFSI) resulting from allegations that PennyMac may have issued materially misleading business information to the investing public.

TORTOLA, British Virgin Islands, June 05, 2026 (GLOBE NEWSWIRE) -- Orca Energy Group Inc. (“Orca” or the “Company” and includes its subsidiaries and affiliates) (TSX-V: ORC.A, ORC.B) today announces that it has filed its condensed consolidated interim (unaudited) financial statements and management’s discussion and analysis for the three month period ended March 31, 2026 (“Q1 2026”) with the Canadian securities regulatory authorities. All amounts are in United States dollars (“$”) unless otherwise stated.

TKROBOTS introduces an AI-powered crypto quantitative trading platform with automated execution, wallet management, daily settlement records, and free trial access for new users.

TERRE HAUTE, Ind., June 05, 2026 (GLOBE NEWSWIRE) -- Hallador Energy Company (Nasdaq: HNRG) (“Hallador” or the “Company”) today announced that its subsidiary, Hallador Power Company, LLC (“Hallador Power”), was selected by the U.S. Department of Energy’s (“DOE”) Hydrocarbons and Geothermal Energy Office to begin award negotiations for up to $27.2 million, in potential federal funding to modernize the Merom Generating Station (“MGS”) located in Merom, Indiana. Total project cost is estimated to be approximately $56.9 million. The comprehensive modernization project is designed to upgrade MGS’s water management systems to position the plant for future federal Effluent Limitation Guidelines (ELG) requirements. This project will help modernize the delivery of reliable and flexible energy to MISO zone 6.

Arbitrum-based prediction market protocol prepares for global expansion with AI-powered market resolution, expanded liquidity infrastructure, and upcoming Version 2 release

GENEVA, June 05, 2026 (GLOBE NEWSWIRE) -- TRON DAO, the community-governed DAO dedicated to accelerating the decentralization of the internet through blockchain technology and decentralized applications (dApps), today announced the spot listing of TRX, the native utility token of the TRON network, on Bitnomial, a  CFTC -regulated U.S. exchange and clearinghouse.

The listing expands access to TRX for U.S. market participants through a regulated trading venue, providing investors and institutions with an additional platform to access the native utility token of the TRON blockchain. TRX supports transactions, smart contract execution, decentralized applications, and network governance across one of the world's most active blockchain ecosystems. TRON is recognized as a leading blockchain for stablecoin activity and digital asset settlement, hosting more than $89 billion in circulating USDT and over $27 billion in total value locked (TVL).

“Bitnomial’s listing of TRX is an important step in expanding access to TRON through regulated U.S. market infrastructure,” said Justin Sun, Founder of TRON. “As demand for compliant digital asset products continues to grow, the availability of TRX on regulated platforms supports broader market access, greater transparency and the continued maturation of the digital asset ecosystem.”

Bitnomial, LLC, headquartered in Chicago, is a derivatives exchange company that owns and operates U.S. CFTC-regulated exchange (DCM), clearinghouse (DCO), and clearing brokerage (FCM) subsidiaries. Bitnomial offers leveraged spot, perpetuals, futures, options, and prediction markets on a single unified exchange and clearinghouse with digital asset margin and settlement capabilities. 

The addition of TRX further expands the range of digital assets available on regulated U.S. financial infrastructure, building on a series of recent developments that have strengthened the institutional foundation of the TRON network. In recent months, TRX became available for custody through Anchorage Digital, the first federally chartered crypto bank in the United States, supporting the expansion of tokenized real-world asset products with top-tier asset managers on the network. 

As digital asset markets continue to evolve, open blockchain networks remain central to expanding access to transparent, permissionless financial infrastructure. The Bitnomial listing reflects continued progress toward making blockchain-based assets more accessible through reliable and established market infrastructure.

BulkQuant introduces a simplified stock quant trading tool designed to help beginners explore AI stock trading bots without coding, complex setup, or advanced strategy configuration.